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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
14.85
Human Site:
S752
Identified Species:
27.22
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S752
K
E
H
E
K
E
K
S
V
S
S
D
R
K
K
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S752
K
E
H
E
K
E
K
S
V
S
S
D
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S752
K
E
H
E
K
E
K
S
V
S
S
D
R
K
K
Dog
Lupus familis
XP_543184
1286
146207
S780
K
E
H
E
K
E
K
S
V
S
S
D
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
A704
R
E
Y
E
T
E
N
A
I
S
S
D
R
K
K
Rat
Rattus norvegicus
NP_001099552
648
74414
Y169
T
C
I
G
T
P
Y
Y
L
S
P
E
I
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
I385
D
C
Q
D
G
S
Q
I
D
R
R
M
E
E
Y
Chicken
Gallus gallus
XP_420401
1281
145243
P767
E
E
Q
E
D
N
H
P
L
L
G
D
R
K
R
Frog
Xenopus laevis
Q7ZZC8
944
104521
D465
F
F
L
N
E
P
V
D
Q
V
S
C
G
D
S
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
G218
L
V
L
K
I
M
S
G
T
F
A
P
I
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
H612
E
K
R
A
W
D
D
H
E
M
P
L
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
H127
L
H
A
N
H
I
L
H
R
D
V
K
C
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
A379
E
V
Q
A
R
V
E
A
E
L
Q
R
H
G
R
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
100
N.A.
60
6.6
N.A.
0
33.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
20
53.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
0
16
0
0
8
0
0
0
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
8
8
8
0
% C
% Asp:
8
0
0
8
8
8
8
8
8
8
0
47
0
8
8
% D
% Glu:
24
47
0
47
8
39
8
0
16
0
0
8
8
8
8
% E
% Phe:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
8
0
0
8
0
8
8
8
% G
% His:
0
8
31
0
8
0
8
16
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
0
8
8
0
8
8
0
0
0
16
0
0
% I
% Lys:
31
8
0
8
31
0
31
0
0
0
0
8
8
54
39
% K
% Leu:
16
0
16
0
0
0
8
0
16
16
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
16
0
8
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
16
0
8
0
0
16
8
0
0
0
% P
% Gln:
0
0
24
0
0
0
8
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
8
0
8
0
0
0
8
8
8
8
47
0
16
% R
% Ser:
0
0
0
0
0
8
8
31
0
47
47
0
0
16
8
% S
% Thr:
8
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
8
8
0
31
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _